本文由小咖机器人翻译整理

期刊来源：N Engl J Med

文献发表时间：2023-12-21

原文链接：https://doi.org/10.1056/NEJMoa2306448

摘要内容如下：

类鼻疽是由类鼻疽伯克霍尔德菌（Burkholderia pseudomallei）引起的一种罕见但可能致命的细菌性疾病，广泛流行于世界各地的热带和亚热带地区。它通常是通过接触受污染的土壤或淡水而获得的。在这次调查之前，还没有从美国大陆的环境中分离出类鼻疽杆菌。在此，我们报告了三名生活在密西西比湾沿岸同一县的患者，他们在3年内出现了类鼻疽。他们感染了相同的西半球类鼻疽杆菌菌株，该菌株是在从其中一名患者的财产中采集的三份环境样本中发现的。这些发现表明，在密西西比湾沿岸地区的环境中，局部获得了类鼻疽。

英文原文如下：

Abstracts

Melioidosis, caused by Burkholderia pseudomallei, is a rare but potentially fatal bacterial disease endemic to tropical and subtropical regions worldwide. It is typically acquired through contact with contaminated soil or fresh water. Before this investigation, B. pseudomallei was not known to have been isolated from the environment in the continental United States. Here, we report on three patients living in the same Mississippi Gulf Coast county who presented with melioidosis within a 3-year period. They were infected by the same Western Hemisphere B. pseudomallei strain that was discovered in three environmental samples collected from the property of one of the patients. These findings indicate local acquisition of melioidosis from the environment in the Mississippi Gulf Coast region.

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